Skin boosters
1 to 2 days of small bumps decide when Rejuran HB Plus Seoul fits your trip
Rejuran fits a short Seoul trip when the injection day comes early in your stay. Its small bumps usually settle within 1 to 2 days, and the clinic is a 2-minute walk from Nonhyeon Station Exit 5.

Written and medically reviewed by Dr. Jang Dong-hoon · Founder & Medical Director
Published · Updated · 12 min read

A Rejuran HB Plus Seoul trip needs at least one full day in the city after the injections, because the small bumps Rejuran leaves usually settle within 1 to 2 days. Skin boosters can usually be done straight after the consultation, so the treatment itself fits into one visit; the planning is about the days around it. The worry most readers bring is practical: flying home with a bumpy face, or getting back to Sydney or Toronto and realising the next session is in Seoul.
Here is what changes the plan at our clinic in Gangnam. I consult, plan and treat in person, with no counsellor selling packages in between, and every first consultation begins with a 3D skin scan. On a short trip that matters, because the scan decides whether Rejuran is the right booster for what your skin shows before you have built a holiday around it.
If you already have dates, send the day you land and the day you fly out on WhatsApp, together with one daylight photo of your face without makeup. You can write in English.
What Rejuran HB Plus is, and how it appears on our menu
Rejuran is a polynucleotide (PN) skin booster: purified DNA fragments injected into the dermis, the layer a sheet mask never reaches.
The polynucleotides in these products are extracted from fish DNA, which is why a fish allergy is one of the first things to mention. A review in Pharmaceutics comparing PN and PDRN describes how these fragments are thought to support tissue repair.
'HB plus' is the name most readers search. If the exact product on the box matters to you, put the name in your first message and ask which formulation the clinic stocks. Our list also includes Rejuran given with Dermashine, a different route for the same product, and which route suits your skin shows on the scan.
Rejuran sits in a wider skin booster and regeneration menu that includes Juvelook, Sculptra, Radiesse, Ultracol and exosome. PN, PLA, PLLA, CaHA, exosomes and collagen each work on a different timeline, which is why the choice of material matters more than the brand. If the scan points away from PN, our Juvelook overview explains one of the alternatives you may hear about.
What is new in the Rejuran line
Rejuran HB Plus is the newest name in the line. A May 2026 report in the Korea Economic Daily describes it as PN combined with hyaluronic acid and the local anaesthetic lidocaine, which is why it stings less than standard Rejuran. The same report lists the line-up as Rejuran, Rejuran i, Rejuran S and HB Plus.
Our price list names Rejuran HB (low-pain type) at 150,000 KRW per 1cc, beside standard Rejuran and Rejuran i at 120,000 KRW per 1cc. Rejuran S is not on the list, so do not plan a trip around it here. The newest name is not automatically the right one: for thin under-eye skin the eye version comes first, and HB is the one to ask about if pain has kept you away.
Prices are from the list of 20 August 2026 and exclude 10% VAT. The final figure is confirmed at consultation, after the 3D Meta-Vu scan and before anything is started.
How many days does Rejuran need in a Seoul itinerary?
Two nights after the injections is a comfortable minimum for most Rejuran HB Plus Seoul plans: one consultation and treatment day, then 1 to 2 days for the bumps to settle before the flight. If the scan suggests adding a treatment with longer downtime, the stay stretches to match. The worked example further down counts the leave days for a trip from Jakarta.
| Day | What happens | Why it matters |
|---|---|---|
| Arrival | Rest, no clinic visit | The clinic is closed on Sundays and public holidays |
| Day 1 (Mon to Sat) | 3D skin scan, consultation, injections if suitable | Boosters can usually follow the consultation directly |
| Day 2 | Bumps usually settling | The clinic is a 2-minute walk from Nonhyeon Station Exit 5 if anything looks unusual |
| Day 3 | Flight home | Most bumps have settled within 1 to 2 days |
Opening hours shape this more than people expect. The clinic runs Monday to Thursday 10:30 to 19:30, Friday 10:30 to 20:30 and Saturday 10:30 to 16:30, with a weekday lunch break from 13:00 to 14:00; Saturdays run without one. Weekends and Friday evenings fill first, so if your only open slot is Saturday morning, message as soon as your dates are set.
A Saturday treatment followed by a Saturday night flight leaves no settling day at all, and Sunday offers no clinic to walk back to. Landing on a Thursday night and treating on Friday gives you Saturday as a buffer while the doors are still open.
Rejuran recovery, hour by hour
| When | What you will likely notice | How to plan around it |
|---|---|---|
| Right after | Small raised bumps where each droplet went, some redness | Leave makeup off until the next day and keep the evening quiet |
| That night | Bumps begin to soften; mild tenderness | Many doctors advise skipping sauna, hard exercise and alcohol |
| Day 1 | Bumps flatter; makeup usually covers what is left | Walking around the city is usually fine |
| Day 2 | Most bumps gone; pinpoint bruises may still show | Check the mirror in daylight before a flight |
| Following weeks | Texture and elasticity change slowly | Judge the result at home, not in Seoul |
There are two clocks here. The bumps are measured in hours or days, the change in skin quality in weeks, and most confusion about recovery comes from mixing them up. Under the eyes, bruises are more likely and can take a week or more to fade, so leave extra days before photos or a flight if the eye area is in the plan. Beyond that buffer, Rejuran rarely needs a recovery programme or extra hotel nights.

A worked example from Jakarta: leave days and flight timing
Readers weighing korea rejuran in Indonesia against a session in Seoul usually ask one thing first: how much leave does it take? For one session, about three working days. Say you fly from Jakarta and land at Incheon on Thursday night. On Friday morning you take the train to Nonhyeon Station on the Sinbundang Line, leave by Exit 5 and walk two minutes to the clinic, where the 3D scan, the consultation and the injections can usually happen in one visit.
| Day | Plan | Leave day? |
|---|---|---|
| Thursday | Fly from Jakarta, land at Incheon at night | Yes |
| Friday | 3D skin scan, consultation, Rejuran if suitable | Yes |
| Saturday | Bumps settling; the clinic is open 10:30 to 16:30 if anything looks unusual | No |
| Sunday | Rest in Seoul; the clinic is closed | No |
| Monday | Flight home | Yes |
The flight home is the date to protect. A Monday departure gives the bumps two full days and keeps Saturday as a day you can still walk back in. If you can only take two days off, a Friday treatment with a Sunday flight still leaves two nights, but Saturday becomes the only day to have anything checked, so book the Friday slot early.
Skin with a history changes the pace, not the calendar. If your skin is tan to brown and once darkened after a laser, Rejuran works without heat, but needle punctures still cause small inflammation. In that case the usual plan is one Rejuran session and no energy-based treatment on the same trip, until the doctor has seen how your skin reacts. Mention your Fitzpatrick type when you send your dates, if you know it.
If session two is going to happen in Indonesia, take home a note of the product name, the number of cc, the areas treated and the date. That note lets a dermatologist in your city continue from the same point, and it is the same record you would need to come back to Seoul.
Three timing mistakes that cost travellers a session
Most timing problems with Rejuran come from treating it like a facial: one visit, done. It behaves more like a course, and the itinerary has to respect that.
- Injecting on the last day. The bumps are expected and usually flatten within 1 to 2 days, but on travel day you have no chance to have anything checked in Seoul. Aim for the first or second day of your stay.
- Expecting the full course in one trip. Studies of polynucleotide injections usually describe a series of sessions spaced weeks apart. You cannot compress that interval into a week. Treat this trip as session one, and decide before you leave when the next session realistically happens.
- Stacking downtime without noticing. Rejuran on its own leaves bumps for 1 to 2 days. Add Fraxel or CO2 and you are looking at three to seven days of redness and flaking; Agnes leaves small scabs for two to four days. The longest downtime in the plan sets your flight date.
Who should wait, and what can go wrong?
Expected effects after Rejuran are small raised bumps at the injection points, redness, tenderness and sometimes bruising, and most of these fade within days. Less common problems include lumps that last longer, infection at an injection site and allergic reactions; any of these needs a doctor to look at it.
A 2026 real-life assessment of high-purification polynucleotide injections, published in the Journal of Cosmetic Dermatology, reported side effects that were mostly mild and short-lived. That is reassuring, and it is also a reason to keep the first days after treatment close to the clinic.
Tell the doctor before treatment if any of these apply:
- a fish allergy, since the polynucleotides come from fish DNA
- isotretinoin in recent months, or any medication that affects healing
- filler or another injection in the same area recently
- pregnancy or breastfeeding
- active acne, a cold sore or broken skin where the injections would go
- a known reaction to local anaesthetics such as lidocaine, if you are asking about HB Plus
- blood-thinning medication or a bleeding disorder, which makes bruising more likely
None of these is automatically a no, and the in-person exam decides whether and when treatment goes ahead. Some simply move the date.
If one of them applies to you, add it to your WhatsApp message with your travel dates: 'fish allergy', 'isotretinoin until March', 'filler in my cheeks in August'. The doctor reviews it and tells you whether it changes the plan or the timing, so you know before you book the flight.
What are the risks and side effects to watch for after you fly home?
By the time you land, the bumps are usually flat or close to it; what remains is watching for anything that does not follow that pattern, and planning the next session. Faint redness or mild tenderness for a few days is common. A lump that grows, pain that increases, warmth, discharge or fever is not, and should be seen promptly by a doctor near you; do not wait on a message.
A few habits make follow-up from abroad easier:
- Take one daylight photo each morning for the first few days, same window, same angle.
- Before you leave the clinic, ask for the product name, the number of cc and the areas treated, so a doctor at home knows exactly what was injected.
- Note the date of your session; the interval to the next one is counted from it.
When you plan session two, the same logic applies: an early treatment day, a buffer before the flight, and a check of whether anything in your skin or medication has changed since the first visit. Arrange follow-up care at home before you travel, so a local doctor already knows what was done.
Getting to the clinic and booking the visit
THE Beautiful Clinic is on the 2nd floor of the Jinryeong Building, 545-12 Gangnam-daero, Seocho-gu, a 2-minute walk from Exit 5 of Nonhyeon Station on the Sinbundang Line. Consultations run in English and Bahasa Indonesia, so you do not need Korean. You can read about Dr. Jang's background or request a slot through the booking page.
Come with clean skin and no makeup if you can; it keeps the 3D scan and the consultation simple. For a Rejuran HB Plus Seoul stop on a longer holiday, that is most of the preparation.
The smallest useful message is two lines: your landing and departure dates, plus anything from the list above that applies to you. If you already know what you want to ask about, tick Rejuran in the booking selector and send that list on WhatsApp.
The Rejuran price guide lists the cost per cc.
The short version
- Plan at least one full day in Seoul after Rejuran; the small bumps usually settle within 1 to 2 days.
- From Jakarta, one session fits about three working days of leave: Thursday, Friday and Monday.
- Boosters can usually be done straight after the consultation, which begins with a 3D skin scan.
- Rejuran works as a course of sessions spaced weeks apart, so treat one trip as session one.
- Mention a fish allergy, recent isotretinoin or recent filler before you book your flight.
Questions patients ask
Is Rejuran HB Plus the same as regular Rejuran?
Both are polynucleotide skin boosters injected into the dermis. 2026 news coverage describes HB Plus as PN with hyaluronic acid and lidocaine, so the injection stings less. On our list, Rejuran HB (low-pain type) is 150,000 KRW per 1cc and standard Rejuran is 120,000 KRW per 1cc, before 10% VAT; which one suits you is decided after the 3D skin scan.
Can I get Rejuran on the same day as my consultation in Seoul?
Often, yes. Skin boosters can usually be done straight after the consultation. Saturday hours are 10:30 to 16:30, and weekends fill first, so message once your dates are set.
How many days of leave does a Rejuran trip from Indonesia need?
About three working days for one session. Fly out on Thursday, have the scan, consultation and injections on Friday, let the bumps settle over the weekend and fly home on Monday. A Monday flight keeps Saturday free to come back to the clinic if anything looks unusual.
How long do the bumps from Rejuran last?
The small bumps at the injection points usually settle within 1 to 2 days. Redness can take a little longer, and under the eyes a bruise can take a week or more to fade. That is why a day or two in Seoul after treatment makes sense before you fly.
When can I wear makeup after Rejuran?
Common advice is to leave makeup off the treated skin for the rest of the day, so the injection points can close. By the next day makeup usually covers what is left of the bumps; if the skin is still irritated, ask at your appointment first.
What should I tell the clinic before a Rejuran appointment?
Mention any fish allergy, recent isotretinoin, recent filler in the same area and any medication that affects healing. Come with clean skin and no makeup if possible. These details can change the timing of treatment.
How many Rejuran sessions should I plan for?
Studies of polynucleotide injections usually describe a series of sessions spaced weeks apart. The number for your skin is set at the consultation after the scan. Plan your first trip as session one and note the date for the next. If that session will happen at home, take a note of the product, cc, areas and date so a local dermatologist can continue the plan.
Results and recovery vary between individuals, and every treatment can have side effects. Prices are from the clinic's price list and are confirmed at consultation. This article is general information, not a diagnosis.
Sources

About the author
Dr. Jang Dong-hoon
Founder & Medical Director
Founder and medical director of THE Beautiful Clinic in Nonhyeon, Gangnam. He sees every patient's skin analysis before a plan is drawn, and reviews every article on this blog against what the clinic actually does.
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